There are numerous symptoms linked to “post-tubal ligation syndrome” –some of these sterilisation side effects are listed below:-

Hot flushes, night sweats

clammy feeling, chills

Irritability, mood swings, sudden tears

Irregular periods; shorter, lighter periods; heavier periods, flooding;

phantom periods, shorter cycles, longer cycles

Loss of libido

Chronic Fatigue

Breast tenderness

Difficulty concentrating, disorientation, mental confusion

Prolapse of uterus do to rapid decrease in oestrogen levels


Weight gain

Pelvic Pain

Hair loss or thinning, head, pubic, or whole body; increase in facial hair

Changes in fingernails: softer, crack or break easier

These symptoms could be linked to a hormone imbalance due to the target or receptor cells, which are located within the fallopian tubes and are vital in the relay of hormonal messages, being destroyed, damaged, and or removed during the surgery. This theory is partly supported by the fact that this “syndrome” seems to be more common after tubal cauterisation which is likely to cause more damage.

Although many authors doubt that the syndrome exists or that there are any sterilisation side effects; a review article1 of 200 English Language articles on the subject suggests that there may be an effect in patients undergoing sterilisation between the ages of 20 and 29 but not above this age.


Many authors have investigated the sequelae of female sterilization. Increased premenstrual distress, heavier and more prolonged menstrual bleeding, and increased dysmenorrhea have been reported. However, failure to control for age, parity, obesity, previous contraceptive use, interval since sterilization, or type of sterilization may have affected study results. Most studies that have controlled for these important variables have not reported significant changes, except in women who undergo sterilization between 20 and 29 years of age.


Tubal sterilization is not associated with an increased risk of menstrual dysfunction, dysmenorrhea, or increased premenstrual distress in women who undergo the procedure after age 30 years. There may be some increased risk for younger women, although they do not appear to undergo significant hormonal changes.”

It is important therefore to assess individuals who believe that they may have this syndrome and to individualise their care before considering what treatments might help.

Treatment Options:

  • Anti-stress medications
  • Antidepressants and psychological counselling
  • Birth control pills
  • Hysterectomy.
  • Tubal reversal repair (which may be a better alternative to a hysterectomy).

Recently, Mr Pickles was asked for his opinion about this condition in an article by the Daily Mail:



1: Fertil Steril. 1998 Feb;69(2):179-86.

Is there any evidence for a post-tubal sterilization syndrome?

Gentile GP, Kaufman SC, Helbig DW.


8 Comments on “Post Tubal Ligation Syndrome – Evidence?”

  1. Hi all

    I had a tubal sterilization in 2018 on my third c section.However since then my health has gone downhill with all the symptoms stated above. I’ve had every test stress test endoscopy lung test and many bloods with no answers. A goitre has grown yet my hormones levels are normal. There is no talk about tubalication syndrome in Ireland . Could I please get some advice and help this has totally changed my life for the worse.

    Many thanks

    1. Dear Susan, I am sorry to hear this. Can you please contact us via the contact page (fill in the form) and Mandy, PA to Mr Pickles will get back to you.

  2. I am 36 and had filshie clip sterilisation in Wales, I have suffered with all mentioned symptoms including flooding which is just exhausting!
    I am having a pelvic scan next week and will go back to my gp with the information you’ve provided as it is just terrible that we are left to suffer after being told it is a simple operation and not being pre-warned of this side effect!
    I feel really disappointed and upset about the situation as the condition is just debilitating.

  3. I’m 38 got sterilised 2 years ago and ever since I’ve had all the symptoms above. Dont feel my doctor takes it serious . Just keeps giving me more and more pills which don’t work . Any advice?

    1. Hi Christina, I am sorry to hear this. I think if you contact Mandy via the contact us page, she can talk about having a consultation with Mr Pickles as a starting point.

  4. Hi I am currently on the waiting list as I was sterilised back in 2016. I am now undergoing mental health help after not suffering with mental health before I had my sterilisation and do think that being sterilised has had a massive impact on my mental health and well-being. And really want my tubal ligation reversed.

  5. Hello, I am 40. I was sterilized 3 years ago after I had my daughter. My symptoms began after I stopped nursing my daughter. The week before my menstrual my eyes dry out so badly I can not sleep. It calms down when I get my period and then it comes back the last couple of days. My menstrual is also longer and heavier then it was prior to being sterilized. My nails are also thin and I have continuous hair breakage. I did not use birth control or anything prior to my kids as it caused my sister to have blood clots. It is frustrating talking to doctors as they claim having your tubes tied or removed doesn’t cause hormonal imbalance, but I know that that is inaccurate because my body tells me otherwise every month. I am miserable. I have spoken to another woman who shared the same symptoms. My Eye doctor verified that hormonal imbalance can cause dry eye. Please help.

Leave a Reply

Your email address will not be published.